A recent study highlighted by the American Academy of Orthopaedic Surgeons (AAOS) has shed light on the potential benefits of testosterone therapy in reducing the risk of hip fractures and improving post-surgical recovery, particularly in older women.
Hip fractures are a serious concern for individuals aged 65 and older, with women disproportionately affected due to osteoporosis and age-related bone loss. According to AAOS, nearly 75% of hip fractures occur in women, and most patients require surgery followed by prolonged rehabilitation. Many lose their independence, needing assistive devices or long-term care.
Emerging evidence suggests that testosterone therapy may play a protective role in bone health. In both men and women, testosterone has been linked to increased bone density and muscle strength, which are critical factors in preventing falls and fractures. Notably, in a cohort of 65-year-old women who received testosterone therapy following hip surgery, researchers observed a marked improvement in recovery outcomes. These women were less likely to require assistive devices such as walkers or canes during rehabilitation, indicating enhanced mobility and strength.
According to the Centers for Disease Control and Prevention (CDC), hip fractures are among the most serious fall-related injuries in older adults. In 2019, 83% of hip fracture deaths were caused by falls, and women accounted for approximately 70% of hip fractures treated in emergency departments or hospitals
While exact one-year mortality rates vary depending on comorbidities and treatment, studies consistently show that up to 20–30% of older adults die within one year of sustaining a hip fracture. Women, despite having a lower short-term mortality risk than men, still face significant long-term risks. The American Academy of Orthopaedic Surgeons (AAOS) emphasizes that prompt surgical treatment and early mobilization are critical to reducing complications such as pneumonia, blood clots, and disorientation, which contribute to mortality.
References:
- American Academy of Orthopaedic Surgeons. Hip Fracture Prevention. OrthoInfo. https://orthoinfo.aaos.org/en/staying-healthy/hip-fracture-prevention
- American Academy of Orthopaedic Surgeons. Activities After Total Hip Replacement. OrthoInfo. https://orthoinfo.aaos.org/en/recovery/activities-after-hip-replacement
- American Academy of Orthopaedic Surgeons. Management of Hip Fractures in Older Adults: Clinical Practice Guideline. https://www.aaos.org/globalassets/quality-and-practice-resources/hip-fractures-in-the-elderly/hipfxcpg.pdf